Brief Information of the Compound and Protein
Compound Name
2-(2-pyridin-3-ylpyrimidin-4-yl)spiro[5,6-dihydro-1H-pyrrolo[3,2-c]pyridine-7,3'-piperidine]-4-one
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PubChem ID
CID: 54583504
Canonical SMILES
O=C1NCC2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cccnc1
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Compound Formula C20H20N6O
Compound Structure
Protein Name
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 18 nM