Brief Information of the Compound and Protein
Compound Name
(S)-1-(4-(7,7-Dimethyl-4-(3-methylmorpholino)-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-(oxetan-3-yl)urea
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PubChem ID
CID: 49858345
SID: 104231567
Canonical SMILES
C[C@H]1COCCN1c1nc(nc2c1COC2(C)C)-c1ccc(NC(=O)NC2COC2)cc1
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Compound Formula C23H29N5O4
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  2
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
2
IC50 = 37 nM
   TI
   LI
   LO
   TS