Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(3-(4-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperazin-1-yl)propyl)-5,11-dihydrodibenzo[b,e][1,4]oxazepine-7-carboxylicacid
    Show/Hide
 PubChem ID
CID: 54581386
Canonical SMILES
Cn1c(cc(=O)n(C)c1=O)N1CCN(CCCN2c3ccccc3COc3ccc(cc23)C(O)=O)CC1
    Show/Hide
Compound Formula C27H31N5O5
Compound Structure
Protein Name
 Protein Info 
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS