Brief Information of the Compound and Protein
Compound Name
Kuwanon A
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PubChem ID
CID: 44258296
SID: 124342940
Canonical SMILES
CC(C)=CCc1c(-c2ccc(O)c3c2OC(C)(C)C=C3)oc2cc(O)cc(O)c2c1=O
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Compound Formula C25H24O6
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 5300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 10600 nM