Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(3R,5R)-1-[2-amino-6-(3-amino-1H-indazol-6-yl)pyrimidin-4-yl]-5-methylpiperidin-3-yl]-N,3,3-trimethylbutanamide
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 PubChem ID
CID: 51354613
SID: 121273563
Canonical SMILES
C[C@@H]1C[C@H](CN(C1)c1cc(nc(N)n1)-c1ccc2c(N)n[nH]c2c1)N(C)C(=O)CC(C)(C)C
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Compound Formula C24H34N8O
Compound Structure
Protein Name
 Protein Info 
3-phosphoinositide-dependent protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase PDK1 subfamily
Uniprot ID
O15530
Gene Name
PDPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
2
IC50 = 116 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.631 nM