Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,5R)-4-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-5-ethyl-2-morpholinecarboxamide
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 PubChem ID
CID: 51354037
SID: 121272939
Canonical SMILES
CC[C@@H]1CO[C@@H](CN1c1cc(nc(NC)n1)-c1ccc2c(N)n[nH]c2c1)C(=O)NC1CCCCC1
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Compound Formula C25H34N8O2
Compound Structure
Protein Name
 Protein Info 
3-phosphoinositide-dependent protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase PDK1 subfamily
Uniprot ID
O15530
Gene Name
PDPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
2
IC50 = 102 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.31 nM