Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1,1-Dimethylethyl{(3R,5R)-1-[2-amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}carbamate
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 PubChem ID
CID: 50909917
SID: 121273561
Canonical SMILES
C[C@@H]1C[C@H](CN(C1)c1cc(nc(N)n1)-c1ccc2c(N)[nH]nc2c1)NC(=O)OC(C)(C)C
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Compound Formula C22H30N8O2
Compound Structure
Protein Name
 Protein Info 
3-phosphoinositide-dependent protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase PDK1 subfamily
Uniprot ID
O15530
Gene Name
PDPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 74 nM
   TI
   LI
   LO
   TS
2
IC50 = 151 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.31 nM