Brief Information of the Compound and Protein
Compound Name
N-[(2S)-2-hydroxy-3-(6-hydroxy-4-oxospiro[3H-chromene-2,3'-piperidine]-1'-yl)propyl]-3,5-dimethyl-N-(2-propan-2-yloxyethyl)-1,2-oxazole-4-sulfonamide
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PubChem ID
CID: 54580179
Canonical SMILES
CC(C)OCCN(C[C@@H](O)CN1CCCC2(C1)CC(=O)c1cc(O)ccc1O2)S(=O)(=O)c1c(C)noc1C
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Compound Formula C26H37N3O8S
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
IC50 = 18600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 300 nM