Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-1-Methyl-5-(2-phenoxymethyl-azetidine-1-sulfonyl)-1H-indole-2,3-dione
    Show/Hide
 PubChem ID
CID: 11509289
SID: 16611219
Canonical SMILES
CN1C(=O)C(=O)c2cc(ccc12)S(=O)(=O)N1CC[C@H]1COc1ccccc1
    Show/Hide
Compound Formula C19H18N2O5S
Compound Structure
Protein Name
 Protein Info 
Caspase-3
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CD clan
>
Cysteine protease C14 family
Uniprot ID
P42574
Gene Name
CASP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3250 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 91.2 nM
2 IC50 = 91.7 nM