Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]sulfonyl}isatin
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 PubChem ID
CID: 5288850
SID: 14805797
Canonical SMILES
CN1C(=O)C(=O)c2cc(ccc12)S(=O)(=O)N1CCC[C@H]1COc1ccccc1
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Compound Formula C20H20N2O5S
Compound Structure
Protein Name
 Protein Info 
Caspase-3
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CD clan
>
Cysteine protease C14 family
Uniprot ID
P42574
Gene Name
CASP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 7670 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.4 nM
2 IC50 = 114 nM
3 IC50 = 119.2 nM
4 IC50 = 120.23 nM
5 IC50 = 10000 nM
6 Ki = 15 nM
7 Ki = 56.1 nM