Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-5-{1-[2-(Phenoxymethyl)pyrrolidinyl]sulfonyl}isatin
    Show/Hide
 PubChem ID
CID: 9821545
SID: 14780465
Canonical SMILES
O=C1Nc2ccc(cc2C1=O)S(=O)(=O)N1CCC[C@H]1COc1ccccc1
    Show/Hide
Compound Formula C19H18N2O5S
Compound Structure
Protein Name
 Protein Info 
Caspase-3
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease CD clan
>
Cysteine protease C14 family
Uniprot ID
P42574
Gene Name
CASP3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 11500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16.9 nM
2 IC50 = 44 nM
3 IC50 = 239.88 nM
4 IC50 = 240 nM
5 Ki = 8.3 nM
6 Ki = 15 nM