Brief Information of the Compound and Protein
Compound Name
3',5-dihydroxy-3,4',7-trimethoxyflavone
    Show/Hide
PubChem ID
CID: 5280682
SID: 14925058
Canonical SMILES
COc1cc(O)c2c(c1)oc(-c1ccc(OC)c(O)c1)c(OC)c2=O
    Show/Hide
Compound Formula C18H16O7
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000756 MCF/MX Homo sapiens (Human)  1
1
IC50 = 680 nM
   TI
   LI
   LO
   TS
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS
CL000145 NCI-H460 Homo sapiens (Human)  1
1
IC50 = 5700 nM
   TI
   LI
   LO
   TS