Brief Information of the Compound and Protein
Compound Name
5-(2-((1H-indazol-5-yl)methylamino)phenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4H-1,2,4-triazol-3-amine
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PubChem ID
CID: 53326441
Canonical SMILES
C(Nc1ccccc1-c1nnc(Nc2ccc3OCCOc3c2)[nH]1)c1ccc2[nH]ncc2c1
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Compound Formula C24H21N7O2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 7300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3100 nM