Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-chloro-6-(4'-cyanobiphenyl-4-ylamino)pyrimidin-2-ylthio)-2-(naphthalen-1-yl)acetic acid
    Show/Hide
 PubChem ID
CID: 53318433
Canonical SMILES
OC(=O)C(Sc1nc(Cl)cc(Nc2ccc(cc2)-c2ccc(cc2)C#N)n1)c1cccc2ccccc12
    Show/Hide
Compound Formula C29H19ClN4O2S
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS