Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,2R)-1-(3,4-dichlorophenyl)-2-((3-(4-(N,N-dimethylsulfamoyl)piperazin-1-yl)azetidin-1-yl)methyl)-N-(4-fluorobenzyl)-N-methylcyclopropanecarboxamide
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 PubChem ID
CID: 53317679
Canonical SMILES
CN(C)S(=O)(=O)N1CCN(CC1)C1CN(C[C@@H]2C[C@@]2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(Cl)c(Cl)c2)C1
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Compound Formula C28H36Cl2FN5O3S
Compound Structure
Protein Name
 Protein Info 
Neuromedin-K receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000051 BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
Ki = 1.9 nM
   TI
   LI
   LO
   TS