Brief Information of the Compound and Protein
Compound Name
N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide
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PubChem ID
CID: 16071896
SID: 24714437
Canonical SMILES
Fc1cnccc1-c1ncc(NC(=O)C2CC2)nc1-c1cccnc1
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Compound Formula C18H14FN5O
Compound Structure
Protein Name
Adenosine receptor A2b
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P29275
Gene Name
ADORA2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
2
Ki = 24 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 24 nM