Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,4,6-trimethyl-N-[(2S)-1-[[6-methyl-1-[4-(propan-2-ylamino)phenyl]indazol-4-yl]amino]propan-2-yl]benzenesulfonamide
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 PubChem ID
CID: 53323259
Canonical SMILES
CC(C)Nc1ccc(cc1)-n1ncc2c(NC[C@H](C)NS(=O)(=O)c3c(C)cc(C)cc3C)cc(C)cc12
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Compound Formula C29H37N5O2S
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 1.995 nM
   TI
   LI
   LO
   TS
2
IC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12.59 nM