Brief Information of the Compound and Protein
Compound Name
3-[4-[[(2S)-2-(cyclopropylsulfonylamino)propyl]amino]-6-methylindazol-1-yl]-N-propan-2-ylbenzamide
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PubChem ID
CID: 53322314
Canonical SMILES
CC(C)NC(=O)c1cccc(c1)-n1ncc2c(NC[C@H](C)NS(=O)(=O)C3CC3)cc(C)cc12
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Compound Formula C24H31N5O3S
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  2
1
IC50 = 1.995 nM
   TI
   LI
   LO
   TS
2
IC50 = 12.59 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15.85 nM