Brief Information of the Compound and Protein
Compound Name
6-[(3S)-1-benzylpiperidin-3-yl]oxyisoquinoline
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PubChem ID
CID: 53320582
Canonical SMILES
C(N1CCC[C@@H](C1)Oc1ccc2cnccc2c1)c1ccccc1
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Compound Formula C21H22N2O
Compound Structure
Protein Name
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
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AGC protein kinase DMPK family
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AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 331.13 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 169.82 nM