Brief Information of the Compound and Protein
Compound Name
6-[(3S)-1-benzylpiperidin-3-yl]oxyisoquinolin-1-amine
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PubChem ID
CID: 16222361
SID: 24904843
Canonical SMILES
Nc1nccc2cc(O[C@H]3CCCN(Cc4ccccc4)C3)ccc12
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Compound Formula C21H23N3O
Compound Structure
Protein Name
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 776.25 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 239.88 nM