Brief Information of the Compound and Protein
Compound Name
1-{4-[1,1-difluoro-2-oxo-2-(1-pyrrolidinyl)ethyl]phenyl}-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole
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PubChem ID
CID: 24826095
SID: 49847453
Canonical SMILES
FC(F)(F)c1nn(c2CCCCc12)-c1ccc(cc1)C(F)(F)C(=O)N1CCCC1
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Compound Formula C20H20F5N3O
Compound Structure
Protein Name
Glutamate receptor 2
Protein Classification
Ion channel
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Ligand-gated ion channel
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Ionotropic glutamate receptor
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AMPA receptor
Uniprot ID
P42262
Gene Name
GRIA2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 19952.62 nM
   TI
   LI
   LO
   TS