Brief Information of the Compound and Protein
Compound Name
1-({2,6-Difluoro-4-[3-(trifluoromethyl)-6,7-dihydropyrano[4,3-c]pyrazol-1(4H)-yl]phenyl}methyl)-2-pyrrolidinone
    Show/Hide
PubChem ID
CID: 24951946
SID: 56249757
Canonical SMILES
Fc1cc(cc(F)c1CN1CCCC1=O)-n1nc(c2COCCc12)C(F)(F)F
    Show/Hide
Compound Formula C18H16F5N3O2
Compound Structure
Protein Name
Glutamate receptor 2
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42262
Gene Name
GRIA2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 19952.62 nM
   TI
   LI
   LO
   TS