Brief Information of the Compound and Protein
Compound Name
4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2-dihydroquinolin-3(4H)-one
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PubChem ID
CID: 11567352
SID: 16669633
Canonical SMILES
Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12
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Compound Formula C24H25ClN2O
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  3
1
EC50 = 7.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.1 nM
   TI
   LI
   LO
   TS
3
IC50 = 36 nM
   TI
   LI
   LO
   TS