Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-{5-Chloro-2-[9-(2-pyrrolidin-1-yl-ethyl)-6,7,8,9-tetrahydro-5-oxa-9-aza-benzocyclohepten-3-ylamino]-pyrimidin-4-ylamino}-3-fluoro-N-methyl-benzamide
    Show/Hide
 PubChem ID
CID: 53325270
Canonical SMILES
CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3N(CCN4CCCC4)CCCOc3c2)ncc1Cl
    Show/Hide
Compound Formula C27H31ClFN7O2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000282 GTL-16
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS