Brief Information of the Compound and Protein
Compound Name
2-[5-Chloro-2-(6,7,8,9-tetrahydro-5-oxa-9-aza-benzocyclohepten-3-ylamino)-pyrimidin-4-ylamino]-3-fluoro-N-methyl-benzamide
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PubChem ID
CID: 50898348
SID: 110267765
Canonical SMILES
CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3NCCCOc3c2)ncc1Cl
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Compound Formula C21H20ClFN6O2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000282 GTL-16 Homo sapiens (Human)  1
1
IC50 = 57 nM
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