Brief Information of the Compound and Protein
Compound Name
2-(4-chlorobenzyl)-1-(4-((S)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl)piperazin-1-yl)-3-(pyrrolidin-1-yl)propan-1-one
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PubChem ID
CID: 53325900
Canonical SMILES
C[C@@H]1SCc2ncnc(N3CCN(CC3)C(=O)C(CN3CCCC3)Cc3ccc(Cl)cc3)c12
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Compound Formula C25H32ClN5OS
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
IC50 = 178 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM