Brief Information of the Compound and Protein
Compound Name
3-(isopropylamino)-1-(4-((S)-5-methyl-5,7-dihydrofuro[3,4-d]pyrimidin-4-yl)piperazin-1-yl)-2-(4-methylbenzyl)propan-1-one
    Show/Hide
PubChem ID
CID: 24889250
SID: 51081746
Canonical SMILES
CC(C)NCC(Cc1ccc(C)cc1)C(=O)N1CCN(CC1)c1ncnc2CO[C@@H](C)c12
    Show/Hide
Compound Formula C25H35N5O2
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
IC50 = 995 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM