Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[1-[2-[1-[2-chloro-4-fluoro-5-(methylsulfamoyl)benzoyl]-4-(3-fluorophenyl)piperidin-4-yl]ethyl]piperidin-4-yl]-N-prop-2-enyl-3-[4-(trifluoromethoxy)phenyl]propanamide
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 PubChem ID
CID: 52942223
Canonical SMILES
CNS(=O)(=O)c1cc(C(=O)N2CCC(CCN3CCC(CC3)N(CC=C)C(=O)CCc3ccc(OC(F)(F)F)cc3)(CC2)c2cccc(F)c2)c(Cl)cc1F
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Compound Formula C39H44ClF5N4O5S
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000149 HOS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS