Brief Information of the Compound and Protein
Compound Name
((3R,4S)-3-((3,5-bis(trifluoromethyl)benzyl)(methyl)amino)-4-phenylpyrrolidin-1-yl)(4-(methylsulfonyl)piperazin-1-yl)methanone
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PubChem ID
CID: 52949416
Canonical SMILES
CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)[C@H]1CN(C[C@@H]1c1ccccc1)C(=O)N1CCN(CC1)S(C)(=O)=O
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Compound Formula C26H30F6N4O3S
Compound Structure
Protein Name
Neuromedin-K receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P29371
Gene Name
TACR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
Ki = 1300 nM
   TI
   LI
   LO
   TS