Brief Information of the Compound and Protein
Compound Name
6-(4-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)butoxy)isoindolin-1-one
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PubChem ID
CID: 24738459
SID: 49631727
Canonical SMILES
Fc1cccc2cccc(N3CCN(CCCCOc4ccc5CNC(=O)c5c4)CC3)c12
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Compound Formula C26H28FN3O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P08908
Gene Name
HTR1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
Ki = 0.0504 nM
   TI
   LI
   LO
   TS
2
Ki = 0.951 nM
   TI
   LI
   LO
   TS