Brief Information of the Compound and Protein
Compound Name
1-[(6S)-3-ethylsulfanyl-6-pyridin-2-yl-6H-[1,2,4]triazino[5,6-d][3,1]benzoxazepin-7-yl]propan-1-one
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PubChem ID
CID: 6402250
Canonical SMILES
CCSc1nnc-2c(O[C@H](N(C(=O)CC)c3ccccc-23)c2ccccn2)n1
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Compound Formula C20H19N5O2S
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 4365.16 nM
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   LI
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   TS