Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-fluoro-2-[5,5,5-trifluoro-4-hydroxy-2-methyl-4-[[(2-methylquinolin-5-yl)amino]methyl]pentan-2-yl]phenol
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 PubChem ID
CID: 21948904
Canonical SMILES
Cc1ccc2c(NCC(O)(CC(C)(C)c3cc(F)ccc3O)C(F)(F)F)cccc2n1
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Compound Formula C23H24F4N2O2
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 12.59 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.162 nM
   TI
   LI
   LO
   TS
3
IC50 = 5.012 nM
   TI
   LI
   LO
   TS
4
IC50 = 12.59 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 6.31 nM
   TI
   LI
   LO
   TS
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5.012 nM
   TI
   LI
   LO
   TS