Brief Information of the Compound and Protein
Compound Name
4-(2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-N-(4-methyl-1-oxo-1H-benzo[d][1,2]oxazin-6-yl)-2-(trifluoromethyl)pentanamide
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PubChem ID
CID: 9805004
SID: 14761126
Canonical SMILES
Cc1noc(=O)c2ccc(NC(=O)C(O)(CC(C)(C)c3cccc4CCOc34)C(F)(F)F)cc12
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Compound Formula C24H23F3N2O5
Compound Structure
Protein Name
Mineralocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 2
Uniprot ID
P08235
Gene Name
NR3C2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 79.43 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 38 nM