Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-fluoro-2-[5,5,5-trifluoro-4-hydroxy-2-methyl-4-[(quinolin-5-ylamino)methyl]pentan-2-yl]phenol
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 PubChem ID
CID: 20786216
SID: 99459144
Canonical SMILES
CC(C)(CC(O)(CNc1cccc2ncccc12)C(F)(F)F)c1cc(F)ccc1O
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Compound Formula C22H22F4N2O2
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 79.43 nM
   TI
   LI
   LO
   TS
2
IC50 = 6.31 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 19.95 nM
   TI
   LI
   LO
   TS