Brief Information of the Compound and Protein
Compound Name
1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-[(quinolin-5-ylamino)methyl]pentan-2-ol
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PubChem ID
CID: 10194889
SID: 15191248
Canonical SMILES
COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cccc2ncccc12)C(F)(F)F
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Compound Formula C23H24F4N2O2
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 25.12 nM
   TI
   LI
   LO
   TS