Brief Information of the Compound and Protein
Compound Name
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[3-(morpholin-4-ylmethyl)-5-(trifluoromethyl)phenyl]urea
    Show/Hide
PubChem ID
CID: 52948336
Canonical SMILES
Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cc(CN5CCOCC5)cc(c4)C(F)(F)F)c(Cl)c3)c12
    Show/Hide
Compound Formula C26H24ClF3N6O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS