Brief Information of the Compound and Protein
Compound Name
1-(3-tert-Butyl-1-methyl-1H-pyrazol-5-yl)-3-{2-chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea
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PubChem ID
CID: 52949957
Canonical SMILES
Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cc(nn4C)C(C)(C)C)c(Cl)c3)c12
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Compound Formula C22H24ClN7O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 260 nM
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