Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}urea
    Show/Hide
 PubChem ID
CID: 52947692
Canonical SMILES
CN1CCN(Cc2cc(NC(=O)Nc3ccc(Oc4ncnc5ccn(C)c45)cc3Cl)cc(c2)C(F)(F)F)CC1
    Show/Hide
Compound Formula C27H27ClF3N7O2
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS