Brief Information of the Compound and Protein
Compound Name
3-[4,4,4-Trifluoro-3-hydroxy-1,1-dimethyl-3-(1H-pyrrolo-[2,3-c]pyridin-2-ylmethyl)butyl]biphenyl-4-ol
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PubChem ID
CID: 46939116
SID: 99447415
Canonical SMILES
CC(C)(CC(O)(Cc1cc2ccncc2[nH]1)C(F)(F)F)c1cc(ccc1O)-c1ccccc1
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Compound Formula C26H25F3N2O2
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 45 nM
2 IC50 = 15 nM