Brief Information of the Compound and Protein
Compound Name
(R)-1-(2-(1-naphthamido)acetyl)pyrrolidin-2-ylboronic acid
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PubChem ID
CID: 15951636
SID: 22423076
Canonical SMILES
OB(O)[C@@H]1CCCN1C(=O)CNC(=O)c1cccc2ccccc12
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Compound Formula C17H19BN2O4
Compound Structure
Protein Name
Prolyl endopeptidase FAP
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S9B subfamily
Uniprot ID
Q12884
Gene Name
FAP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  2
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
2
Ki = 7.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.3 nM