Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorobenzyl)propylamine
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 PubChem ID
CID: 4369359
SID: 14904024
Canonical SMILES
N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
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Compound Formula C16H15F6N5O
Compound Structure
Protein Name
 Protein Info 
Dipeptidyl peptidase 8
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S9B subfamily
Uniprot ID
Q6V1X1
Gene Name
DPP8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1820 nM
2 IC50 = 19000 nM
3 IC50 = 32000 nM
4 IC50 = 32800 nM
5 IC50 = 48000 nM
6 IC50 = 51000 nM
7 IC50 = 69000 nM
8 IC50 > 20000 nM
9 IC50 > 50000 nM
10 IC50 > 100000 nM