Brief Information of the Compound and Protein
Compound Name
(R)-1-(2-(1-oxoisoindolin-2-yl)acetyl)pyrrolidin-2-ylboronic acid
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PubChem ID
CID: 44418251
Canonical SMILES
OB(O)[C@@H]1CCCN1C(=O)CN1Cc2ccccc2C1=O
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Compound Formula C14H17BN2O4
Compound Structure
Protein Name
Prolyl endopeptidase FAP
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SC clan
>
Serine protease S9B subfamily
Uniprot ID
Q12884
Gene Name
FAP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 93 nM
2 Ki = 7.5 nM