Brief Information of the Compound and Protein
Compound Name
5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-methyl-1-(2-methylpropyl)-6-(quinolin-4-ylmethyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione
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PubChem ID
CID: 5282545
SID: 17384840
Canonical SMILES
CC(C)Cn1c2sc(Cc3ccnc4ccccc34)c(C(=O)N3CC[C@@H](O)C3)c2c(=O)n(C)c1=O
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Compound Formula C26H28N4O4S
Compound Structure
Protein Name
Monocarboxylate transporter 1
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC16 family of monocarboxylate transporters
Uniprot ID
P53985
Gene Name
SLC16A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000127 INS-1 Rattus norvegicus (Rat)  1
1
Ki = 3.311 nM
   TI
   LI
   LO
   TS
CL000001 Jurkat Homo sapiens (Human)  1
1
Ki = 30.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.8 nM