Bioactivity Information | MolBiC

Brief Information of the Compound and Protein

Compound Name

Compound Info

1,4,5-Insp3

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PubChem ID

CID: 439456

SID: 14929378

Canonical SMILES	O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O Show/Hide
Compound Formula	C6H15O15P3

Compound Structure

Protein Name

Protein Info

Inositol 1,4,5-trisphosphate receptor type 1

Protein Classification

Ion channel

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Ligand-gated ion channel

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IP3 receptor

Uniprot ID

P29994

Gene Name

ITPR1

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000302	DT40 Cell Line Info	Gallus gallus (Chicken)	15
1	EC50 = 20 nM	TI LI LO TS
2	EC50 = 22.3 nM	TI LI LO TS
3	EC50 = 23 nM	TI LI LO TS
4	EC50 = 24.8 nM	TI LI LO TS
5	EC50 = 26.6 nM	TI LI LO TS
6	EC50 = 40.8 nM	TI LI LO TS
7	EC50 = 85 nM	TI LI LO TS
8	Kd = 0.21 nM	TI LI LO TS
9	Kd = 0.27 nM	TI LI LO TS
10	Kd = 0.45 nM	TI LI LO TS
11	Kd = 0.46 nM	TI LI LO TS
12	Kd = 0.98 nM	TI LI LO TS
13	Kd = 2.32 nM	TI LI LO TS
14	Kd = 2.64 nM	TI LI LO TS
15	Kd = 12.5 nM	TI LI LO TS