Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[6-[4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridin-3-yl]thiophene-2-carboxamide
    Show/Hide
 PubChem ID
CID: 2741895
Canonical SMILES
O=C(Nc1ccc(N2CCN(c3ncccc3C(F)(F)F)CC2)nc1)c1cccs1
    Show/Hide
Compound Formula C20H18F3N5OS
Compound Structure
Protein Name
 Protein Info 
Mothers against decapentaplegic homolog 3
Protein Classification
Transcription factor
Uniprot ID
P84022
Gene Name
SMAD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
Potency ~ 23109.3 nM
   TI
   LI
   LO
   TS