Brief Information of the Compound and Protein
Compound Name
2-Amino-6-({2-oxo-2-[4-(trifluoromethyl)phenyl]ethyl}sulfanyl)-4-(3-thienyl)pyridine-3,5-dicarbonitrile
    Show/Hide
PubChem ID
CID: 46839104
SID: 99222422
Canonical SMILES
Nc1nc(SCC(=O)c2ccc(cc2)C(F)(F)F)c(C#N)c(-c2ccsc2)c1C#N
    Show/Hide
Compound Formula C20H11F3N4OS2
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 3600 nM
   TI
   LI
   LO
   TS