Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-1-cyclohexyl-1-methylurea
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 PubChem ID
CID: 46891026
Canonical SMILES
CN(C1CCCCC1)C(=O)Nc1ccc(cc1)-c1cnc2c(cnn2c1N)-c1cccc(c1)N1CCN(C)CC1
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Compound Formula C31H38N8O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase Lck
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Src family
Uniprot ID
P06239
Gene Name
LCK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 333 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8 nM