Brief Information of the Compound and Protein
Compound Name
2-Methoxymethoxy-5-(2-methylquinolin-7-yl)benzonitrile
    Show/Hide
PubChem ID
CID: 46888004
Canonical SMILES
COCOc1ccc(cc1C#N)-c1ccc2ccc(C)nc2c1
    Show/Hide
Compound Formula C19H16N2O2
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 596 nM
   TI
   LI
   LO
   TS
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 = 294 nM
   TI
   LI
   LO
   TS