Brief Information of the Compound and Protein
Compound Name
5-((6-Methylpyridin-2-yl)ethynyl)nicotinonitrile
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PubChem ID
CID: 46861851
SID: 99289838
Canonical SMILES
Cc1cccc(n1)C#Cc1cncc(c1)C#N
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Compound Formula C14H9N3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
Ki = 1.5 nM
   TI
   LI
   LO
   TS
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS