Brief Information of the Compound and Protein
Compound Name
4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]butyramide
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PubChem ID
CID: 46888204
Canonical SMILES
CC1(C)N(CCCC(N)=O)C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F
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Compound Formula C17H17F3N4O2S
Compound Structure
Protein Name
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CL000141 LNCaP Homo sapiens (Human)  2
1
IC50 = 55 nM
   TI
   LI
   LO
   TS
2
IC50 = 400 nM
   TI
   LI
   LO
   TS